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- Keywords Cyclovirobuxine D;Glutamate transporter;6-Hydroxy-dopamine;PC12 cells; 环维黄杨星-D;谷氨酸转运体;6-羟基多巴胺;PC12细胞;
- Keywords cyclovirobuxine D;right ventricular papillary muscle;electrophysiology; 环维黄杨星;右心室乳头肌;电生理;
- Keywords cyclovirobuxine D;derivative;sulfonic acid amide;polyethylene glycol;bioactivity; 环维黄杨星D;衍生物;磺酰胺;聚乙二醇;生物活性;
- Keywords cyclovirobuxine D;myocardial infarct size;hemodynamics;biochemistry;canine; 关键词环维黄杨星D;心肌梗死;血流动力学;生物化学;犬;
- Keywords Cyclovirobuxine D;Tablets;Acid dye colorimetry;Bormethynol blue;Determination of contenet;Uniformity of dosage form; 黄杨宁;片剂;含量测定;酸性染料比色法;溴麝香草酚蓝;含量均匀度;
- AIM:To study the new separating technology of cyclovirobuxine D. 目的:研究环维黄杨星D新的分离方法。
- An acid dye colorimetry method was developed for the determination of cyclovirobuxine D and its tablets . 首次建立了黄杨宁酸性染料比色法。
- RESULT:The monocase of cyclovirobuxine D could be obtained by the chemical separating method. 结果:用化学分离方法可得到纯度较高的环维黄杨星D。
- Mechanisms of cyclovirobuxine D on APD prolongation in rat ventricular myocytes. 海马干细胞分化的神经元电生理特征的初步探讨。
- METHOD:Acetylation of the total alkaloids of buxus gave tri-acetylated cyclovirobuxine D followed by hydroxylsis to produce the target compound. 方法:黄杨木总生物碱通过酰化、酸溶分离得到环维黄杨星D三乙酰化物,经水解得目标物。
- Results Cyclovirobuxine D is the major component in Huangyangning and cyclobuxine D and cyclovirobuxine C are the two related alkaloids. 结论经色谱分析、分离和光谱鉴定,确证黄杨宁主要由具有相同骨架结构的同系生物碱组成。
- Method Ethylcellulose (EC) was used as a basic material and mixed with cyclovirobuxine D (CVB-D) and other materials to prepare HSRT. 方法以乙基纤维素(EC)作为缓释材料与黄杨宁原料药混合做固体分散物,再加入其他辅料制备黄杨宁缓释片。
- Methods According to rational drug design principle, a series of cyclovirobuxine D analogues were prepared, and their bioactivities were tested. 方法根据合理药物设计原理,设计合成目标化合物,并研究其生物活性。
- Conclusion Endurance lacking oxygen activity and antiarrhythmia effects of some analogues of cyclovirobuxine D were tested.Some compounds showed better activity than cy... 结论选取部分环维黄杨星D新衍生物进行耐缺氧、抗心律失常药理实验,结果表明部分化合物药理活性优于环维黄杨星D。
- This method can be used to determine not only the content of material and dosage form of cyclovirobuxine D, but also uniformity of dosage form.It is highly sensitive , accurate and simple. 该方法可用于黄杨宁原料、片剂的含量测定及片剂的含量均匀度检查，具有灵敏度高、准确度好、操作简便等优点。
- Keywords HPLC;ELSD;gradient elution;cyclovirobuxine D; 关键词HPLC;蒸发光散射检测器;梯度洗脱;环维黄杨星D;
- Keywords synthesis;cyclovirobuxine D;water-soluble;polyethylene glycol; 合成;环维黄杨星D;水溶性;聚乙二醇;
- Keywords buxine;cyclovirobuxine D;pharmacokinetics;bioequivalence;solid phase extraction;LC/MS/MS; 黄杨宁;环维黄杨星D;药代动力学;生物等效性;固相萃取;液质联用技术;
- Keywords
cyclovirobuxine D;TLC;prccolumn derivatization fluorescence;RP-HPLC;nonaqueous titration; 环维黄杨星D;薄层色谱;荧光衍生化;高效液相色谱;非水滴定; - Keywords Huang Yang Ning;Cyclovirobuxine D;Titration in nonaqueous solvent;content determination; 黄杨宁;环常绿黄杨碱D;非水溶液滴定;含量测定;
